Preliminary Phytochemical Analysis and Wound Healing Activity from the Leaves of Cocculus hirsutus Diels

DOI:

https://doi.org/10.37285/ijpsn.2009.2.3.13

Authors

  • Panda Bikash Ranjan
  • Mohanta S.R
  • Sii S.
  • Das G. K.

Abstract

In qualitative phytochemical analysis of petroleum ether, chloroform and methanol extracts of the leaves of Cocculus hirsutus Diels, the important secondary plant metabolites detected are Carbohydrates, Steroids, Glycosides, Tannins, Saponins and Flavonoids. The methanol extract and fresh leaves juice are subjected to wound healing activity in incision and excision wound models taking Soframycin sulphate as standard. The results revealed that the methanol extract ointment 10%w/w has highest wound healing potency among the test groups and is comparable with the standard and thus the results offer a scientific support to the treatment of traditional healers of this region.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Keywords:

Wound healing, Cocculus hirsutus, Excision, Incision

Downloads

Published

2009-11-30

How to Cite

1.
Ranjan PB, S.R M, S. S, G. K. D. Preliminary Phytochemical Analysis and Wound Healing Activity from the Leaves of Cocculus hirsutus Diels. Scopus Indexed [Internet]. 2009 Nov. 30 [cited 2024 Jul. 2];2(3):675-8. Available from: http://ijpsnonline.com/index.php/ijpsn/article/view/904

Issue

Section

Short Communication

References

Indian Medicinal Plants, Edited by Warrior P.K. et al., Orient Longman Pvt. Ltd., 2003, P-138.

Kirtikar K.R. and Basu B.D., Indian Medicinal Plants, Sri Satguru Publication, New Delhi, 3rd revised enlarged edition 2002, V-1, P-120.

Badole S., Patel N., Badhankar S., Jain B., Bharadwaj S., Antihyperglycemic Activity of aqueous extract of leaves of Cocculus hirsutus(L)Diels in alloxan induced diabetic mice., Ind. J. of Pharmacol., V-38(1), 49-53, (2006).

Panda B.R., Mohanta S.R., Misra U.S., Kar S., Panda B.K., Chakraborty p., Antimicrobial activity of the leaves of Cocculus hirsutus., Indian Drugs, 44(2), 108-110, (2007).

Mortone J.P. and Malone M.H., Evaluation of vulnerary activity by and open wound procedure in rats. Arch. Int. Pharmacodyn., 196(6), 117-136,(1972).

Ehlirch H.P. and Hunt T.K.,The effect of cortisone and anabolic steroids on the tensile strength of healing wounds. J.Ann.Surg.170(2), 203-206, (1969).

Mukherjee P.K., Quality Control of Herbal Drugs, Business Horizons Publications, 1st edition, 2002, p546-549.

Somaya L.I., Shode F.O., Ramnanan P. and Nadar A., Antihypertensive, antiatherosclerotic and antioxidant activity of triterpinoids isolated from Olea europaea, subspecies africana leaves. J. Ethnopharmacol., 84, 299, (2003).

Tsuchiya H., Sato M., Miyazaki T., Fuziwara S. , Tanigaki S., Ohyama M., Tanaka T. and Linuma M., Comparative study on the antimicrobial activity of phytochemical flavones against methicillin-resistant Staphylococcus aureus. J. Ethnopharmacol., 50, p-27, (1996).

Gulcin I., Mshvidadze V., Gepdiremen A. and Elias R., Antioxidant activity of saponins isolated from Ivy: alpha-hederin, hederasaponin-C, hederacolchiside-E and hederacolchiside-F. Planta Medica, 70(6), 561, (2004).

Marjorie M.C., Plant products as antimicrobial agents. Clinical Microbiology Reviews, 12(4), 564, (1999).

Ganapaty S., DashG.K., Subburaju T.and Suresh P., Diuretic, laxative and toxicity study of cocculus hirsutus aerial parts., Fitoterapia, 73(1), 28-31, (2002).