Development and Characterization of Pomegranate-Based Nanoparticles for Drug Delivery Applications

DOI:

https://doi.org/10.37285/ijpsn.2018.11.1.6

Authors

  • Vinay C H
  • Gulzar Ahmed Mohammed
  • Prakash Goudanavar
  • Ankit Acharya Acharya

Abstract

The main objective of the present work was to prepare pomegranate peel extract based nano particles by chemical complexation method. Ethanolic extracts of pomegranate peel were prepared by using Soxhlet apparatus and evaluated for phyto-chemical constituents. Qualitative analysis showed that pomegranate peel extract showed positive results for alkaloids, anthraquinones, saponins and terpenoids.The percentage moisture content and pH of the extract was found to be 72% and 3.6 respectively. A zeta potential and particle size of prepared nanoparticles was found in the range of -24.6 to– 34.5 mV and 118.6 nm to 231.7 nm, respectively. These range confirms that obtained particles were in nano range, i.e. <500 nm size. SEM results indicated the formation of nanoparticles and were relatively spherical in shape. Energy dispersive spectrometry (EDS) analysis confirms the presence of AgNPs. Further the study will be extended for anti-microbial and wound healing activities.        

 

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Keywords:

Pomegranate peel extract, Qualitative analysis, Nanoparticles, Energy spectrometry

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Published

2018-01-31

How to Cite

1.
C H V, Mohammed GA, Goudanavar P, Acharya AA. Development and Characterization of Pomegranate-Based Nanoparticles for Drug Delivery Applications. Scopus Indexed [Internet]. 2018 Jan. 31 [cited 2024 Nov. 21];11(1):3984-9. Available from: https://ijpsnonline.com/index.php/ijpsn/article/view/351

Issue

Vol. 11 No. 1 (2018): January-February 2018

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC

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