Terpenoids from Dicliptera chinensis (L.) Nees Grown in Vietnam and their Anti-inflammatory Activities




  • Loi Vu Duc
  • Tung Bui Thanh
  • Tung Nguyen Huu


The main goal of this study was to isolate and screen the therapeutic potential of some terpenoids from Dicliptera chinensis (L.) Nees grown in Vietnam. From the leaves of Dicliptera chinensis (L.) Nees (Acanthaceae) collected in Nam Dinh province, one new terpenoid (1) together with five known (2-6) were isolated by chromatographic methods. These compounds were identified as 6-hydroxy-1,12-oleanadien-3-on (1), 1β,4β-dihydroxyeudesm-11-ene (2), 3β-hydroxylup-20(29)-en (3), stigmast-5,22-dien-3-β-ol (4), rutaevine (5), mangiferin (6). All of them were isolated from this plant for the first time. Compound 4 showed signficant potential for COX-2 inhibitory effects with IC50 values of 7.32± 1.82 µg/mL. These pilot results suggest the potential of Dicliptera terpenoids for treating inflamatory conditions. 


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Dicliptera chinensis, 1β,4β-dihydroxyeudesm-11-ene, 3β-hydroxylup-20 (29)-20(29)-en, Stigmast-5,22-dien-3-β-ol, rutaevine, mangiferin




How to Cite

Duc LV, Thanh TB, Huu TN. Terpenoids from Dicliptera chinensis (L.) Nees Grown in Vietnam and their Anti-inflammatory Activities. Scopus Indexed [Internet]. 2018 Mar. 31 [cited 2024 Apr. 20];11(2):4052-6. Available from: http://ijpsnonline.com/index.php/ijpsn/article/view/363



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