Nanosensors: Unveiling the Invisible-Advancement in Drug Detection

DOI:

https://doi.org/10.37285/ijpsn.2024.17.3.1

Authors

  • Nikrita Ph.D. Scholar
  • Bikash Medhi Professor, Department of Pharmacology

Abstract

Introduction 

Nanotechnology represents the designing, synthesis, characterization, and application of materials and devices whose size ranges in nanoscale is 1-100nm1. Which can be defined by the term, technology on the nanoscale. With the change in structure and size nanoscale material possesses distinct enhanced physiochemical properties due to dramatic changes from the bulk material to reduced material of size below 100nm2. Nanotechnology applications were first observed in Lycurgus glass and Medieval church windows which changed color in different lighting conditions due to nanoparticles with size ranges from 50-100nm. However, laureate Richard Feynman, an American physicist is considered the father of nanotechnology3. The nanoscale development has various importance involving possessing a high surface area which makes it suitable for drug delivery and other applications, it possesses numerous microscopic and macroscopic properties, and they form the combination of material science with biology, other than all the mentioned importance of nanotechnology the macroscopic materials made up of the nanoscale material possess high density which makes the nanomaterial batter conductor4. Different methods have been adopted to synthesize nanomaterials such as Top-Down Approach, Bottom-Up Approach, and Hybrid Approach3-5. 

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Keywords:

NANOSENSORS, DRUG DETECTION, nanomaterials

Published

2024-06-30

How to Cite

1.
Nikrita, Bikash Medhi. Nanosensors: Unveiling the Invisible-Advancement in Drug Detection. Scopus Indexed [Internet]. 2024 Jun. 30 [cited 2024 Dec. 21];17(3):7327-30. Available from: https://ijpsnonline.com/index.php/ijpsn/article/view/5368

References

Silva GA. Introduction to nanotechnology and its applications to medicine. Surgical Neurology. 2004 Mar 1;61(3):216–20.

Nasrollahzadeh M, Sajadi SM, Sajjadi M, Issaabadi Z. An Introduction to Nanotechnology. In: Interface Science and Technology [Internet]. Elsevier; 2019 [cited 2024 Mar 30]. p. 1–27. Available from: https://linkinghub.elsevier.com/retrieve/pii/B9780128135860000018

Bayda S, Adeel M, Tuccinardi T, Cordani M, Rizzolio F. The History of Nanoscience and Nanotechnology: From Chemical–Physical Applications to Nanomedicine. Molecules. 2020 Jan;25(1):112.

Mansoori GA, Soelaiman TAF. Nanotechnology—an introduction for the standards. J ASTM Int. 2005 Jan 1;2:1–21.

Harish V, Ansari MM, Tewari D, Gaur M, Yadav AB, García-Betancourt ML, et al. Nanoparticle and Nanostructure Synthesis and Controlled Growth Methods. Nanomaterials. 2022 Jan;12(18):3226.

A.K L, Viswanath IV, Bhagavathula D, Boddeti G, Venu R, Murthy YLN. Review on nanomaterials: Synthesis and applications. Materials Today: Proceedings. 2019 Aug 1;18.

Harish V, Tewari D, Gaur M, Yadav AB, Swaroop S, Bechelany M, et al. Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications. Nanomaterials. 2022 Jan;12(3):457.

Javaid M, Haleem A, Singh RP, Rab S, Suman R. Exploring the potential of nanosensors: A brief overview. Sensors International. 2021 Jan 1;2:100130.

Swierczewska M, Liu G, Lee S, Chen X. High-sensitivity nanosensors for biomarker detection. Chem Soc Rev. 2012 Apr 7;41(7):2641–55.

Salvati E, Stellacci F, Krol S. Nanosensors for early cancer detection and for therapeutic drug monitoring. Nanomedicine. 2015 Dec;10(23):3495–512.

Garrido E, Alfonso M, Díaz De Greñu B, Marcos MD, Costero AM, Gil S, et al. A Sensitive Nanosensor for the In Situ Detection of the Cannibal Drug. ACS Sens. 2020 Sep 25;5(9):2966–72.

Nanosensor for Sensitive Detection of the New Psychedelic Drug 25I‐NBOMe - Garrido - 2020 - Chemistry – A European Journal - Wiley Online Library [Internet]. [cited 2024 Apr 9]. Available from: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.201905688

Gopalan D, Pandey A, Alex AT, Kalthur G, Pandey S, Udupa N, et al. Nanoconstructs as a versatile tool for detection and diagnosis of Alzheimer biomarkers. Nanotechnology. 2021 Jan;32(14):142002.

Pal A, Kaswan K, Barman SR, Lin YZ, Chung JH, Sharma MK, et al. Microfluidic nanodevices for drug sensing and screening applications. Biosens Bioelectron. 2023 Jan 1;219:114783.

Bardajee GR, Sharifi M, Mahmoodian H. Novel CMC-CdTe / ZnS QDs Nanosensor for the Detection of Anticancer Drug Epirubicin. J Fluoresc. 2021 May;31(3):651–8.

Garrido E, Climent E, Marcos MD, Sancenón F, Rurack K, Martínez-Máñez R. Dualplex lateral flow assay for simultaneous scopolamine and “cannibal drug” detection based on receptor-gated mesoporous nanoparticles. Nanoscale. 2022 Sep 29;14(37):13505–13.

Amiri A, Faridbod F, Zoughi S. Selective and Rapid Optical Detection of Citalopram Using a Fluorescent Probe Based on Carbon Quantum Dots Embedded in Silica Molecularly Imprinted Polymer. J Fluoresc. 2023 Jul 26;

Belal F, Mabrouk M, Hammad S, Barseem A, Ahmed H. A Novel Eplerenone Ecofriendly Fluorescent Nanosensor Based on Nitrogen and Sulfur-Carbon Quantum Dots. J Fluoresc. 2021 Jan;31(1):85–90.

Kaya SI, Kurbanoglu S, Yavuz E, Demiroglu Mustafov S, Sen F, Ozkan SA. Carbon-based ruthenium nanomaterial-based electroanalytical sensors for the detection of anticancer drug Idarubicin. Sci Rep. 2020 Jul 6;10(1):11057.

H K, R G, Le J, D G, K F. SERS Detection of Multiple Antimicrobial-Resistant Pathogens Using Nanosensors. Analytical chemistry [Internet]. 2017 Dec 5 [cited 2024 Apr 11];89(23). Available from: https://pubmed.ncbi.nlm.nih.gov/28985467/

A surface enhanced Raman scattering based colloid nanosensor for developing therapeutic drug monitoring - PubMed [Internet]. [cited 2024 Apr 11]. Available from: https://pubmed.ncbi.nlm.nih.gov/30193149/

Deng J, Zhao S, Liu Y, Liu C, Sun J. Nanosensors for Diagnosis of Infectious Diseases. ACS Appl Bio Mater. 2021 May 17;4(5):3863–79.

Liu X, Lei H, Hu Y, Fan X, Zhang Y, Xie L, et al. A turn-on fluorescent nanosensor for H2S detection and imaging in inflammatory cells and mice. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Sep 5;297:122739.

Bekdemir A, Tanner EEL, Kirkpatrick J, Soleimany AP, Mitragotri S, Bhatia SN. Ionic Liquid-Mediated Transdermal Delivery of Thrombosis-Detecting Nanosensors. Adv Healthc Mater. 2022 Jun;11(11):e2102685.

Pathak K, Saikia R, Sarma H, Pathak MP, Das RJ, Gogoi U, et al. Nanotheranostics: application of nanosensors in diabetes management. J Diabetes Metab Disord. 2023 Jun;22(1):119–33.

Nanotechnology and Early Cancer Detection and Diagnosis - NCI [Internet]. 2017 [cited 2024 May 18]. Available from: https://www.cancer.gov/nano/cancer-nanotechnology/detection-diagnosis

Callahan M. First-of-its-kind nanosensor could help diagnosis and treatment of neurological disease [Internet]. Northeastern Global News. 2021 [cited 2024 May 18]. Available from: https://news.northeastern.edu/2021/04/12/first-of-its-kind-nanosensor-could-help-diagnosis-and-treatment-of-neurological-disease/

Upconversion-based nanosensor for chemotherapy drug detection [Internet]. 2022 [cited 2024 May 18]. Available from: https://www.nanowerk.com/nanotechnology-news2/newsid=60747.php

Chavan AM, Gilda DSS. A Review on: Pharmaceutical Application of Nanosensor. 2021;9(5).

Most read articles by the same author(s)