Psoriasis: A Non-Communicable Chronic Autoimmune Inflammatory Skin Disorder, Affecting the Quality of Life
DOI:
https://doi.org/10.37285/ijpsn.2023.16.6.8Abstract
Psoriasis is grouped under chronic, non-communicable skin conditions. This inflammatory condition is way beyond physical manifestations, but more psychological and emotional to patients whose social and interpersonal relationships are affected. Termed to simple words psoriasis affects the patients ‘Quality of Life’. The primary concern of health care is to prioritize the stigma caused by this skin condition. Incidence has no origin instead this condition has several factors associated with it and the cause of the disease in each patient differs. Genetic and immunological conclusions of psoriasis have a strong base to consider the incidence of the disease. This review discusses the history, epidemiology, Prevalence, triggers of the disease, FDA-approved drugs, and several herbal drugs that have shown pharmacological activity against psoriasis.
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Psoriasis, Autoimmune disease, quality of life, epidemiology, approved drugsPublished
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Mark Lebwohl (2003): Psoriasis; Lancet 361; 1197- 1204.
Kamlesh Kumar Singh, Surendra Tripathy: Natural Treatment Alternative for Psoriasis: A Review on Herbal Resources. Journal of Applied Pharmaceutical Science 2014; 4 (11): 114-121.
Jeffrey M. Weinberg (2007): Treatment of Psoriasis; Mile stones in Drug therapy: Birkhauser, NY.
I.M. Michalek, B. Loring, S.M. John (2017); A systematic review of worldwide epidemiology of psoriasis. JEADV: 31, 205–212
Gibbs S. Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol. 1996;35(9):633–9.
Danielsen K, Olsen AO, Wilsgaard T, Furberg AS. Is the prevalence of psoriasis increasing? A 30-year follow-up of a populationbased cohort. Br J Dermatol. 2013;168:1303–10.
Global risk on psoriasis. World Health Organization. Noncommunicable diseases and their risk factors. https://www.who.int/ncds/ management/psoriasis/en/
Dr Oleg Chestnov; Global report on Psoriasis: WHO: ISBN 978 92 4 156518 9
Report: New WHO report: 100 million people affected by psoriasis, action needed to provide care, overcome discrimination. World health organization https://www.who.int/ncds/management/feature_story_on_psoriasis_2.pdf?ua=1
Len Seiden (2015): The History of Psoriasis; National Psoriasis foundation: https://www.psoriasis.org/advance/history-psoriasis
Fox H (1915) Dermatology of the ancients. JAMA 65: 469
Gunter Burg, MD, Michael Geiges, MD (2014), Lepra vulgaris. History of Psoriasis: J Turk Acad Dermatol; 8 (3): 1483r1
A Divya Preetha. An investigative outlook on ubiquitous healthcare for Psoriasis patients. IJSRD.2016;4(5):1715-1721.
Radcliffe-Crocker, H. (1883) Diseases of the Skin (3rd edn), H.K. Lewis.
Perera GK, Di Meglio P, Nestle FO. Psoriasis. Annu Rev Pathol. 2012; 7():385-422.
Beutner, E.H. (ed.) (1982) Autoimmunity in Psoriasis, CRC Press
Jan D. Bos and Menno A. De Rie(1999), The pathogenesis of psoriasis: immunological facts and speculations. Immunology today; 20(1): 40-46.
Ortonne JP. Recent developments in the understanding of the pathogenesis of psoriasis. Br J Dermatol. 1999;140(54):1–7
Bos JD, De Rie MA. The pathogenesis of psoriasis: Immunological facts and speculations. Immunol Today. 1999;20:40–6
Chang EY, Hammerberg C, Fisher G, Baadsgaard O, Ellis CN, Voorhees JJ, et al. T cell activation is potentiated by cytokines released by lesional psoriatic, but not normal, epidermis. Arch Dermatol. 1992;128:1479–85.
Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture: Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes. J Clin Invest. 1995 ;95: 317-327
Toruniowa B, Jabłońska S. Mast cells in the initial stages of psoriasis.. Arch Dermatol Res. 1988; 280(4):189-93.
Takeda H, Okubo Y, Koga M, Aizawa K. Lipid analysis of peripheral blood monocytes in psoriatic patients using Fourier-transform infrared microspectroscopy. J Dermatol. 2001 Jun; 28(6):303-11.
Brunner PM, Koszik F, Reininger B, Kalb ML, Bauer W, Stingl G. Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages. J Allergy Clin Immunol. 2013 Nov; 132(5):1184-1193.e8.
Zawada AM, Rogacev KS, Schirmer SH, Sester M, Böhm M, Fliser D, Heine GH. Monocyte heterogeneity in human cardiovascular disease. Immunobiology. 2012 Dec; 217(12):1273-84.
Stratis A, Pasparakis M, Rupec RA, Markur D, Hartmann K, Scharffetter-Kochanek K, Peters T, van Rooijen N, Krieg T, Haase I. Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J Clin Invest. 2006 Aug; 116(8):2094-104.
Gupta R, Debbaneh MG, Liao W. Genetic Epidemiology of psoriasis. Curr Dermatol Rep . 2014;3(1):61–78.
Lomholt G. Psoriasis, prevalence, spontaneous course and genetics. .E.C. Gad, 1963.
Richard son Sk, Gerlfand JM. Update on natural history and systemic treatment of Psoriasis. Adv Dermatol, 2008:24: 171-96.
Nanda A, Kaur I, Kumar B. Childhood Psoriasis: An epidemiological survey of 112 patients. Pediatr Dermatol 1990; 7: 19- 21.
Gupta R, Debbaneh MG, Liao W. Genetic Epidemiology of psoriasis. Curr Dermatol Rep . 2014;3(1):61–78.
Sagoo GS, Cork MJ, Patel R, et al. Genome-wide studies of psoriasis susceptibility loci: a review. J Dermatol Sci 2004;35(3):171–9.
Peters BP, Weissman FG, Gill MA. Pathophysiology and treatment of psoriasis. Am J Health Syst Pharm 2000;57:645-59.
Zbytek B, Pikula M, Slominski RM, Mysliwski A, Wei E, Wortsman J,et al. Corticotropin-releasing hormone triggers differentiation in HaCaT keratinocytes. J Dermatol. 2005; 152(3):474-80.
Kim JE, Cho DH, Kim HS, Kim HJ, Lee JY, Cho BK, Park HJ. Expression of the corticotropin-releasing hormone-proopiomelanocortin axis in the various clinical types of psoriasis. Exp Dermatol. 2007 Feb; 16(2):104-9
Lugi Naldi. Psoriasis and smoking: links and risks. Psoriasis (Auckl).2016;6:65-71.
Farkas A, Kemény L. Psoriasis and alcohol: is cutaneous ethanol one of the missing links?. Br J Dermatol. 2010; 162(4):711-6.
Naldi L, Chatenoud L, Linder D, Belloni Fortina A, Peserico A et al. Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case-control study. J Invest Dermatol. 2005 Jul; 125(1):61-7.
Tagami H. Triggering factors. Clin Dermatol . 1997;15(5):677–685.
Rademaker M, Agnew K, Anagnostou N, Andrews M et al. Psoriasis and infection. A clinical practice narrative. Australas J Dermatol. 2019;60(2):91-98.
Nilmarie Ayala-Fontánez,David C Soler, and Thomas S McCormick. Current knowledge on psoriasis and autoimmune diseases. Psoriasis (Auckl). 2016; 6: 7–32.
Howa Yeung, Junko Takeshita, Nehal N. Mehta,Stephen E. Kimmel. Psoriasis severity and the prevalence of major medical co-morbidities: a population-based study. JAMA Dermatol. 2013; 149(10): 1173–1179.
Jeffrey M. Weinberg: Treatment of Psoriasis:Brikhayser; Springer 2008
Laws PM, Young HS. Topical treatment of psoriasis. Expert Opin Pharmacother. 2010 Aug; 11(12):1999-2009.
Menter A. The status of biologic therapies in the treatment of moderate to severe psoriasis. Cutis. 2009 Oct; 84(4 Suppl):14-24.
Raboobee N, Aboobaker J, Jordaan HF, Sinclair W, Smith JM, et al. Guideline on the management of psoriasis in South Africa. Working Group of the Dermatological Society of South Africa. S Afr Med J. 2010 Apr; 100(4 Pt 2):257-82.
Laws PM, Young HS. Topical treatment of psoriasis. Expert Opin Pharmacother. 2010 Aug; 11(12):1999-2009.
Yamashita M, Katsumata M, Iwashima M, Kimura M, Shimizu C et al. T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex. J Exp Med. 2000 Jun 5; 191(11):1869-79.
Zeichner JA, Lebwohl M. Potential complications associated with the use of biologic agents for psoriasis. Dermatol Clin. 2007 Apr; 25(2):207-13, vii.
Menter A. The status of biologic therapies in the treatment of moderate to severe psoriasis. Cutis. 2009 Oct; 84(4 Suppl):14-24.
Luigi Barrea, Maria Cristina Savanelli, Carolina Di Somma, Maddalena Napolitano et al. Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist. Rev Endocr Metab Disord. 2017; 18(2): 195–205.
Raboobee N, Aboobaker J, Jordaan HF, Sinclair W, Smith JM, Todd G, Weiss R, Whitaker D. Guideline on the management of psoriasis in South Africa. Working Group of the Dermatological Society of South Africa. S Afr Med J. 2010 Apr; 100(4 Pt 2):257-82.
Menter A, Gottlieb A, Feldman SR, Van Voorhees AS, Leonardi CL, Gordon KB, Lebwohl M, Koo JY, Elmets CA, Korman NJ, Beutner KR, Bhushan R. Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics. J Am Acad Dermatol. 2008 May; 58(5):826-50.
Nilmarie Ayala-Fontanez, David C Soler, ThomasS McCormick. Current knowledge on psoriasis andautoimmune diseases. Psoriasis (Auckl). 2016; 6: 7–32.
FDA approved drugs, National psoriasis foundation: https://www.psoriasis.org/phases/fda-approved.
Kamlesh Kumar Singh, Surendra Tripathy: Natural Treatment Alternative for Psoriasis: A Review on Herbal
Dermavant Sciences GmbH, tapinarof for the treatment of plaque Psoriasis in Adults, NCT03983980, US national Library Medicine, Clinical trials.gov. https://clinicaltrials.gov/ct2/show/record/NCT03983980.
Resources: Journal of Applied Pharmaceutical Science.2014; Vol. 4 (11); 114-121.
Shikang Meng, Zibei Lin, Yan Wang, Zhenping Wang, Ping Li, and Ying Zheng; Psoriasis therapy by Chinese medicine and modern agents. Chin Med .2018; 13:16
Brown AC, Koett J, Johnson DW, Semaskvich NM, Holck P, Lally D, Cruz L, Young R, Higa B, Lo S. Effectiveness of kukui nut oil as a topical treatment for psoriasis. Int J Dermatol. 2005;44:684-687.
Dhanabal SP, Priyanka Dwarampudi L, Muruganantham N, Vadivelan R. (2012) Evaluation of the antipsoriatic activity of Aloe vera leaf extract using a mouse tail model of psoriasis. Phytother Res. 26:617–19.
Maharjan H. Radha Nampoothiri P.Laxmipriya: Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine 2015: 5(1): 21-26
Saelee C, Thongrakard V, Pencomnao T. Effects of high medicinal herb extract with anti-psoriatic activity on the expression of NF-KB signaling biomarkers in HaCaT keratinocytes. Molecules. 2011; 16(3); 908-32.
Anirban Chouni, and Santanu Paul: A Review on Phytochemical and Pharmacological Potential of Alpinia galangal. Pharmacognosy Journal. 2018: 10(1); 09-15.
Sunitha Parlapally Neeraja Cherukupalli et al.: Chemical profiling and anti-psoriatic activity of methanolic extract of Andrographis nallamalayana . J.L.Ellis. Natural Product Research 2016: 30(11); 1256-1261
Bhuchar S, Katta R, Wolf J. Complementary and alternative medicine in dermatology: An overview of selected modalities for the practicing dermatologist. Am J Clin Dermatol.2012: 13; 311-17
Dr. Amit Kumar Dutta. Review on the uses and good side of custard apple from the tribal area of chattisgarh.WJPPS.2017.6(2) 1397-1403.
Chalinee Ronpirin, Thitiporn Charueksereesakul, Visa Thongrakard and Tewin Tencomnao. Effects of ethanolic extract of Annona squamosa L. leaves on the expression of EGFR.ournal of Chemical and Pharmaceutical Research, 2014, 6(4):791-797.
S.S Pandey, A.K Jha, Vineet Kaur. Aqueous extract of neem leaves in treatment of Psoriasis Vulgaris. Indian J Dermatol Venereol Leprol. 1994, 60(2); 63-67.
MurugananthamN, Basavaraj KH, Dhanabal SP, Praveen TK, Shamasundar NM, Rao KS. Screening of Caesalpinia bonduc leaves for antipsoriatic activity. J Ethnopharmacol. 2011;133(2), 897.
Vigasini Subbiah, Pannaga Nagaraja, Priya Narayan, Holenarasipur Gundu Rao Nagendra.(2019) Evaluation of Pharmacological Properties of Caesalpinia bonducella Seed and Shell Extract.Pharmacogn J 11(1),150-154.
U.Wollina, J Hercogova, M. Floranelli, S Gianfaldoni et al.,(2016) Scalp Psoriasis: Apromising Ntural treatment. Journal of biological regulators &homeostatic agents.30(2),103-108.
Brown DJ, Dattner AM.(1998) Medical journal article on herbs for common skin conditions. Arch Dermatol,134,1401-1404.
Deng S, May BH, Zhang AL, Lu C, Xue CC.,(2013) Plant extracts for the topical management of psoriasis: a systematic review and meta-analysis. Br J Dermatol.169, 769-782.
Sanjay K R, Bankim C T, Bikash R K,(2017)Natural Green Alternatives to Psoriasis Treatment– A Review. Glob J Pharmaceu Sci. 4(1), 555631.
Bernstein JE, Parish LC, Rapaport M, Rosenbaum MM, Roenigk HH. Effects of topically applied capsaicin on moderate and severe psoriasis vulgaris. J Am Acad Dermatol. 1986.15(3): 504-507.
Tram NT, Son HL (2015) Assessment of Anti-psoriatic Activity of Cassia fistula L. Extract Incorporated Cream British Journal of Pharmaceutical Research.2015; 5(6): 370-378.
Manmohan Singhai, Niraj Kansara. Cassia tora Linn Cream Inhibits Ultraviolet-B-Induced Psoriasis in Rats. international scholarly research network. 2012. ID. 346510: 1-6.
Vijayalakshmi, Geetha Madhira. Anti- Psoriatic activity of flavinoids from Cassia tora leaves using the rat ultraviolet B ray photodermatitis model. Revista Brasileira de Farmacognosia. 2014; 24(3): 322-329.
Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Brzezińska M. Centella asiatica in cosmetology. Postepy Dermatol Alergol. 2013;30:46-49.
Gelmini F, Beretta G, Anselmi C, Centini M, Magni P, Ruscica M, Cavalchini A, Maffei Facino R. GC-MS profiling of the phytochemical constituents of the oleoresin from Copaifera langsdorffii Desf. and a preliminary in vivo evaluation of its antipsoriatic effect. Int J Pharm. 2013;440:170-178
Joe B, Lokesh BR. Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages. Lipids, 1997; 32:1173-1180
Vijayalakshmi. A, V Ravichandiran and K Masilamani Anti-Psoriatic Activity of Flavonoids from the Bark of Givotia rottleriformis Iranian Journal of Pharmaceutical Sciences 2014: 10 (3): 81- 94
Najafizadeh P, Hashemian F, Mansouri P, Farshi S, Surmaghi MS, Chalangari R. The evaluation of the clinical effect of topical St Johns wort (Hypericum perforatum L.) in plaque type psoriasis vulgaris: a pilot study. Australas J Dermatol. 2012; 53: 131-135.
Laura McDermott BA, Raman Madan MD, Reena Rupani MD, and Daniel Siegel MD: A Review of Indigo Naturalis as an Alternative Treatment for Nail Psoriasis. J Drugs Dermatol. 2016;15(3):319-323.
Sushil K. Chouhan HS, Sahu AN, Narayan G.Singh: Assessment of in vitro antipsoriatic activity of selected Indian medicinal plants Pharmaceutical Biology. 2015: 53( 9): 1295-1301.
Gulliver WP, Donsky HJ: A report on three recent clinical trials using Mahonia aquifolium 10% topical cream and a review of the worldwide clinical experience with Mahonia aquifolium for the treatment of plaque psoriasis. Am J Ther. 2005 ;12(5):398-406.
Murti K, Panchal MA, Gajera V, Solanki J. Pharmacological properties of Matricaria recutita: A review. Pharmacologia. 2012: 3:348-351
Safayhi H, Sabieraj J, Sailer ER, Ammon HP. Chamazulene: An antioxidant-type inhibitor of leukotriene B4 formation. Planta Medica, 1994: 60: 410-413.
Pazyar N, Yaghoobi R: Tea tree oil as a novel antipsoriasis weapon. Skin Pharmacol Physiol. 2012;25(3):162-3
Roopashree TS, Raman Dang, Shobha Rani RH, Narendra C (2008) Antibacterial activity of antipsoriatic herbs: Cassia tora, Momordica charantia and Calendula officinalis International Journal of Journal of Applied Research in Natural Products.2008:1(3);20- 28.
Dwarampudi LP, Palaniswamy D, Nithyanantham M, Raghu PS. Anti-psoriatic activity and cytotoxicity of ethanolic extract of Nigella sativa seed. Pharmacogn Mag, 2012; 8:268-72.
Sushil K. Chouhan HS, Sahu AN, Narayan G.Singh : Assessment of in vitro antipsoriatic activity of selected Indian medicinal plants Pharmaceutical Biology . 2015: 53( 9): 1295-1301.
Divakara P., Nagaraju B., Buden R. P., Sekhar H. S.and Ravi C. M; Antipsoriatic activity of Ayurvedic ointment containing aqueous extract of the bark of Pongamia Pinnata using the rat ultraviolet ray photodermatitis model Advancement in Medicinal Plant Research. 2013: 1(1); 8-16.
Kotiyal JP, Sharma D : Phytochemical studies of Psoralea species, Bulletin of Medico-Ethnobotanical Research, 1992: 13, 209–223.
Devi Priya M, E.A. Siril: Traditional and Modern Use of Indian Madder (Rubia cordifolia L.): An Overview. Int. J. Pharm. Sci. Rev. Res. 2014: 25(1) : 154-164
Reuter J, Merfort I, Schempp CM. Botanicals in dermatology: an evidence-based review. Am J Clin Dermatol. 2010;11:247- 267.
Sabir S, Arsshad M, Asif S, Chaudhari SK. An insight into medicinal and therapeutic potential of Silybum marianum (L.) Gaertn. Int J Biosci. 2014; 4:104-115.
Vijayalakhsmi A, Ravichandiran V, Malarkadi V, Nirmala S, Jaykumari S. Screening of flavonoid “quercetin” from the rhizome of Smilax china Linn. For anti-psoriatic activity. Asian Pac J Trop Biomed, 2012: 269-275.
Shrivastava S, Sindhu KR, Kumar S, Kumar P. Antipsoriatic and phytochemical evaluation of Thespesia populnea bark extracts. Int J Pharm Pharm Sci., 2009; 1: 176-185.
Brown AC, Hairfield M, Richards DG, McMillin DL, Mein EA, Nelson CD. Medical nutrition therapy as a potential complementary treatment for psoriasis – Five case reports. Altern Med Rev. 2004; 9: 297-307.
Bhuchar S, Katta R, Wolf J. Complementary and alternative medicine in dermatology: An overview of selected modalities for the practicing dermatologist. Am J Clin Dermatol.2012; 13:311-317.
M.N. Shiva Kameshwari and G. Paramasivam; Urginea indica and its role in psoriasis: A Review. Int. J. of Pharm. & Life Sci. (IJPLS); 2012: 3(12): 2236-2242
Singh SK, Chouhan HS, Sahu AN, Narayan G: Assessment of in vitro antipsoriatic activity of selected Indian medicinal plants. Pharm Biol. 2015;53(9):1295-301
Dhanabal SP, Baskar Anand Raj, MurugananthamN. Praveen TK, RAghu PS; Screening of Wrightia tinctoria leaves for Anti psoriatic activity. Hygeia.J.D. Med.2012: vol.4 (1): 73-78.
Gupta MA, Schork NJ, Gupta AK, Kirkby S, Ellis CN. Sucidal Ideation in Psoriasis. Int J Dermatol. 1993 Mar; 32(3):188-90.
Ghada M, El-Hanafy, Shereen Madgi and EmanR.Said. Dermatology Life Quality Index Correlation with Different Demographic and Clinical Factors in Psoriasis Patients: A Hospital-Based Cross-Sectional Study. Med.J. CairoUniv,Vol.89(1), March:243-250, 2021.
Joel M. Gelfand, Steven R Feldman, Robert S Stern, John Thomas, Tara Rolstad, David Margolis. Determinants of Quality of life in patients with psoriasis with Psoriasis. A study from US population. Journal of the American Academy of Dermatology,vol, 51(5), 2004, 704-708.
Meneguin, S., de Godoy, N.A., Pollo, C.F. et al. Quality of life of patients living with psoriasis: a qualitative study. BMC Dermatol 20, 22 (2020).
Kwan, Z., Bong, Y.B., Tan, L.L. et al. Determinants of quality of life and psychological status in adults with psoriasis. Arch Dermatol Res 310, 443–451 (2018).
