Nanoformulation Loaded with Essential Oils via Ultrasonication Technique: Overview, Challenges, and Prospects
DOI:
https://doi.org/10.37285/ijpsn.2022.15.3.10Abstract
Essential oils have been used for virucidal, bactericidal, fungicidal, antiparasitic, insecticidal, and other therapeutic properties like analgesic, sedative, spasmolytic, anti-inflammatory, and locally anaesthetic remedies since the Medieval Era. Essential oils are complex mixtures of a variety of volatile molecules which includes terpenoids, phenol-derived aromatic components, and aliphatic components. These molecules are used in the pharmacological, cosmetic, sanitary, food, and agricultural sectors for multiple applications. The stability and bioactivity of essential oils, on the other hand, impact their efficacy. The ultrasonication procedure is one of the most effective ways to preserve essential oils. Improved water solubility, effective degradation protection, and the prevention of volatile component evaporation are just a few of the benefits. This article focuses on nanotechnology's most significant contributions to essential oils formulated using the Ultrasonication process. The chemical makeup of essential oils, the Ultrasonication technique's basis, the physicochemical characteristics of nanoformulation loaded with essential oil, and their contemporary uses are all highlighted. Essential oils can perform better than chemically synthesized drugs. As compared to certain other formulation techniques, oil nanoencapsulation has been noted as a cost-effective approach, and the ultrasonication approach is a simpler, less energy-consuming, more repeatable, and broadly valid method for the encapsulation of essential oils.
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Essential oils, Nanoencapsulation, Ultrasonication, Drug Delivery System
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