Nanosuspension: A New Horizon in the Drug Delivery System
DOI:
https://doi.org/10.37285/ijpsn.2022.15.5.9Abstract
Solubility is one of the major concerns in a lot of drug formulations. Since the majority of new drug molecules belong to the BCS II (Biopharmaceutical Classification of Drug) they often lead to poor bioavailability and ultimately affect the drug's effectiveness. The majority of new drug molecules are insoluble and hence poorly bioavailable. Because of these limitations, the proportion of newly discovered drugs reaching the market is decreasing. Nano-suspension emerges as one of the novel solutions for these problems. As it helps in delivering poorly water-soluble drugs, due to their all-around features and unique advantages. The distinctive features of nanosuspensions allow them to be used in a variety of dosage forms, including mucoadhesive hydrogels, nanogels, etc. The present review article provides information regarding the introduction to nanosuspensions, the advantages, and disadvantages of nanosuspensions, different methods of their preparations, and numerous practical applications in drug delivery.
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Nanosuspension, Dissolution, Surfactant, Solubility, Bioavailability
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