Novel Vesicular Carriers: Proniosomes

DOI:

https://doi.org/10.37285/ijpsn.2023.16.5.10

Authors

  • Bhawana Sharma Department of Pharmaceutics, Bhupal Nobles University, Udaipur
  • Amul Mishra Department of Pharmaceutics, Bhupal Nobles University, Udaipur
  • Piush Sharma Maharishi Arvind College of Pharmacy, Ambabari Circle, Ambabari
  • Shiv Garg Maharishi Arvind College of Pharmacy, Ambabari Circle, Ambabari, Jaipur-302023, India
  • Abhishekh Dwivedi Maharishi Arvind College of Pharmacy, Ambabari Circle, Ambabari, Jaipur
  • Savita Rathore Maharishi Arvind College of Pharmacy, Ambabari Circle, Ambabari, Jaipur

Abstract

Vesicular systems have been receiving a lot of interest as a carrier for advanced drug delivery. Encapsulation of the drug in vesicular structures can be expected to prolong the duration of the drug in the systemic circulation and to reduce toxicity by selective up-taking. Drug delivery systems using colloidal particulate carriers such as liposomes or niosomes have proved to possess distinct advantages over conventional dosage forms because the particles can act as drug reservoirs, and can carry both hydrophilic drugs by encapsulation or hydrophobic drugs by partitioning these drugs into hydrophobic domains and modification of the particle composition or surface can adjust the drug release rate and/or the affinity for the target site. Although niosomes as a carrier have shown advantages such as being cheap and chemically stable, they are associated with problems related to physical stability such as fusion, aggregation, sedimentation and leakage on storage. All methods traditionally used for the preparation of niosomes are time-consuming and many involve specialized equipment.

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Keywords:

Proniosome, Sufactant, Niosomes, Vesicular Drug Delivery

Published

2023-09-15

How to Cite

1.
Sharma B, Mishra A, Sharma P, Garg S, Dwivedi A, Rathore S. Novel Vesicular Carriers: Proniosomes. Scopus Indexed [Internet]. 2023 Sep. 15 [cited 2024 Feb. 26];16(5):7011-23. Available from: https://ijpsnonline.com/index.php/ijpsn/article/view/2577

References

Sachan AK, Kumar S, Dwivedi T, A Review Article on Proniosome: As A Drug Carrier , Asian Journal of Pharmaceutical Research and Development. 2021; 9(4):128-131. DOI: http://dx.doi.org/10.22270/ ajprd.v9i41010

El-Laithy, H. M., Shoukry, O., & Mahran, L. G.. Novel sugar esters proniosomes for transdermal delivery of vinpocetine: preclinical and clinical studies. European Journal of Pharmaceutics and Biopharmaceutics, 2011; 77(1): 43-55.

Hu, C., & Rhodes, D. G. Proniosomes: a novel drug carrier preparation. International journal of pharmaceutics. 1999; 185(1): 23-35.

Walve JR, Rane BR, Gujrathi NA. Proniosomes: A surrogate carrier for improved transdermal drug delivery system. Int J Res Ayurveda Pharm. 2011; 2:743–50.

Pandey, N. Proniosomes and ethosomes: New prospect in transdermal and dermal drug delivery system. International Journal of Pharmaceutical Sciences and Research. 2011; 2(8): 1988-1996.

Mahdi, J., Effionora, A., & Joshita, D. Preparation of Maltodextrin DE 5-10 based ibuprofen Proniosomes. Majalah Ilmu Kefarmasian. 2004; I(1): 10-20.

Kumar, G. P., & Rajeshwarrao, P. Nonionic surfactant vesicular systems for effective drug delivery—an overview. Acta Pharmaceutica Sinica B. 2011; 1(4): 208-219.

Yadav, K., Yadav, D., Saroha, K., Nanda, S., Mathur, P., & Syan, N. Proniosomal Gel: A provesicular approach for transdermal drug delivery. Der Pharmacia Lettre. 2010; 2(4): 189-198.

Annakula, D., Errabelli, M. R., Jukanti, R., Bandari, S., & Veerareddy, P. R. Provesicular drug delivery systems: An overview and appraisal. Archives of Applied Science Research. 2010; 2(4): 135-146.

Akhilesh, D., Faishal, G., & Kamath, J. V. Comparative study of carriers used in proniosomes. International Journal of Pharm Chemical Science. 2012; 3: 6-12.

Pandey, N. Proniosomes and ethosomes: New prospect in transdermal and dermal drug delivery system. International Journal of Pharmaceutical Sciences and Research. 2011; 2(8): 1988-1996.

El-Laithy, H. M., Shoukry, O., & Mahran, L. G. Novel sugar esters proniosomes for transdermal delivery of vinpocetine: preclinical and clinical studies. European Journal of Pharmaceutics and Biopharmaceutics. 2011; 77(1): 43-55.

Gupta, A., Prajapati, S. K., Balamurugan, M., Singh, M., & Bhatia, D. Design and development of a proniosomal transdermal drug delivery system for captopril. Tropical Journal of Pharmaceutical Research. 2007; 6(2): 687-693.

Kumar, K., & Rai, A. K. Development and Evaluation of Proniosomes as a promising drug carrier to improve transdermal drug delivery. International Research Journal of Pharmacy. 2011; 2(11): 71-74.

S. S. Suryawanshi*1, P. P.Patil1, R. G. Gaikwad2, S. S. Mali3, S. L. Pol4, PRONIOSOMES: MODERN DRUG DELIVERY SYSTEM, Pharmaceutical Resonance. 2021; 4(1): 7-18.

Walve, J. R., Rane, B. R., Gujrathi, N. A., Bakaliwal, S. R., & Pawar, S. P. Proniosomes: a surrogated carrier for improved transdermal drug delivery system. International Journal of Research in Ayurveda and Pharmacy. 2011; 2(3): 743-750.

Saroha, Kamal & Nanda, Sanju & Yadav, N. Proniosome gel: Potential carrier system in topical/transdermal delivery for drugs and cosmetics/cosmeceuticals. Pharmaceutical Reviews. 2010; 8.

Akhilesh, D., Hazel, G., & Kamath, J. V. Proniosomes–A propitious provesicular drug carrier. International Journal of Pharmacy and Pharmaceutical Science Research. 2011; 1(3): 98-103.

Goyal, C., Ahuja, M., & Sharma, S. K. Preparation and evaluation of anti- inflammatory activity of gugulipid-loaded proniosomal gel. Acta Poloniae Pharmaceutica. 2011; 68(1): 147-150.

Mokhtar, M., Sammour, O. A., Hammad, M. A., & Megrab, N. A. Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from pronio-somes. International Journal of Pharmaceutics. 2008; 361(1): 104-111.

Ciotti, S. N., & Weiner, N. Follicular liposomal delivery systems. Journal of Liposome Research. 2002; 12(1-2): 143-148.

Fang, J. Y., Yu, S. Y., Wu, P. C., Huang, Y. B., & Tsai, Y. H. In vitro skin permeation of estradiol from various proniosome formulations. International Journal of Pharmaceutics. 2001; 215(1): 91-99.

Abd-Elbary, A., El-Laithy, H. M., & Tadros, M. I. Sucrose stearate-based proniosome-derived niosomes for the nebulisable delivery of cromolyn sodium. International Journal of Pharmaceutics. 2008; 357(1): 189-198.

Blazek–Welsh, A. I., & Rhodes, D. G. SEM imaging predicts quality of niosomes from maltodextrin-based proniosomes. Pharmaceutical Research. 2001; 18(5): 656-661.

Yoshioka, T., Sternberg, B., & Florence, A. T. Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 40, 60 and 80) and a sorbitan triester (Span 85). International Journal of Pharmaceutics. 1994; 105(1): 1-6.

Blazek-Welsh, A. I., & Rhodes, D. G. Maltodextrin-based proniosomes. AAPS Pharm SciTech. 2001; 3(1): 1-8.

Solanki, A., Parikh, J., & Parikh, R. Preparation, characterization, optimization, and stability studies of aceclofenac proniosomes. Iranian Journal of Pharmaceutical Research. 2010; 237-246.

Hu, C., & Rhodes, D. G. Proniosomes: a novel drug carrier preparation. International Journal of Pharmaceutics. 1999; 185(1): 23-35.

Vora, B., Khopade, A. J., & Jain, N. K. Proniosome based transdermal delivery of levonorgestrel for effective contraception. Journal of Controlled Release. 1998; 54(2): 149-165.

Puglia, C., Trombetta, D., Venuti, V., Saija, A., & Bonina, F. Evaluation of in‐vivo topical anti‐inflammatory activity of indometacin from liposomal vesicles. Journal of Pharmacy and Pharmacology. 2004; 56(10): 1225-1232.

Junyaprasert, V. B., Teeranachaideekul, V., & Supaperm, T. Effect of charged and non-ionic membrane additives on physicochemical properties and stability of niosomes. AAPS PharmSciTech. 2008; 9(3): 851- 859.

Rowe, R. C., Sheskey, P. J., & Quinn, M. E. (Eds.) Handbook of pharmaceutical excipients (Vol. 6, p. 888). London: Pharmaceutical press. 2009; 580-584.

Adnan Azeem, Nilu Jain, Zeenat Iqbal, Farhan Jalees Ahmad, Mohammad Aqil, and Sushama Talegaonkar, Pharmaceutical Development and Technology. 2008; 13: 155–163.

Kumari, R., Verma, K., Verma, A., Yadav, G. K., & Maurya, S. D. Proniosomes: A key to improved drug delivery. Journal of Drug Delivery and Therapeutics. 2014; 56-65.

Ibrahim, M. M. A., Sammour, O. A., Hammad, M. A., & Megrab, N. A. In vitro evaluation of proniosomes as a drug carrier for flurbiprofen. AAPS Pharm SciTech. 2008; 9(3): 782-790.

Alsarra, I. A., Bosela, A. A., Ahmed, S. M., & Mahrous, G. M. Proniosomes as a drug carrier for transdermal delivery of ketorolac. European Journal of Pharmaceutics and Biophar-maceutics. 2005; 59(3): 485-490.

Varshosaz, J., Pardakhty, A., Mohsen, S., & Baharanchi, H. Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate. Drug Delivery. 2005; 12(2): 75-82.

Müller, R. H., Radtke, M., & Wissing, S. A. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Advanced Drug Delivery Reviews. 2002; 54: S131- S155.

Alsarra, I. A., Bosela, A. A., Ahmed, S. M., & Mahrous, G. M. Proniosomes as a drug carrier for transdermal delivery of ketorolac. European Journal of Pharmaceutics and Biopharma-ceutics. 2005; 59(3): 485-490.

Varshosaz, J., Pardakhty, A., Mohsen, S., & Baharanchi, H. Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate. Drug Delivery. 2005; 12(2): 75-82.

Thakur, R., Anwer, M. K., Shams, M. S., Ali, A., Khar, R. K., Shakeel, F., & Taha, E. Proniosomal transdermal therapeutic system of losartan potassium: development and pharmacokinetic evaluation. Journal of Drug Targeting. 2009; 17(6): 442-449.

Kute, A., Goudanavar, P., Hiremath, D., & Reddy, S. R. Development and Characterization of Perindopril Erbumine Loaded Proniosomal Gel. Asian Journal of Pharmaceutical Sciences. 2012; 2(2): 54-58.

Sudhamani, T., Ganesan, V., Priyadarsini, N., & Radhakrishnan, M. Formulation and evaluation of ibuprofen loaded maltodextrin based proniosome. International Journal of Biopharmaceutics. 2010; 1(2): 75-81.

Goyal, C., Ahuja, M., & Sharma, S. K. Preparation and evaluation of anti- inflammatory activity of gugulipid-loaded proniosomal gel. Acta Pol Pharm. 2011; 68(1): 147-150.

Solanki, A. B., Parikh, J. R., & Parikh, R. H. Formulation and optimization of piroxicam proniosomes by 3-factor, 3-level Box-Behnken design. AAPS PharmSciTech. 2007; 8(4), 43-49.

Alam, M. I., Baboota, S., Kohli, K., Ali, J., & Ahuja, A. Pharmacodynamic evaluation of proniosomal transdermal therapeutic gel containing celecoxib. ScienceAsia. 2010; 36: 305-311.

Jiang X, Liu L, Li SS, Zhang B, Li XL, Liu ZG, Liu Q. Preparation of paeonol transdermal delivery systems based on proniosomes-based ointment and its pharmacokinetics characters. Zhongguo Zhong Yao Za Zhi. 2014 Jun; 39(11): 2131-5. Chinese. PMID: 25272857

Yadav K, Yadav D, Nanda S, Saroha K. Curcumin proniosomal/niosomal formulation, method for its preparation and use thereof. Indian Patent 1288/DEL/2012

Garg M, Joon M. Novel Proniosomal Gel of Withania Somnifera. Indian Patent 3228/DEL/2012

Garg M, Garg P. Novel Ursolic Acid Loaded Proniosomal Gel and Method of Preparation Thereof. Indian Patent 3231/DEL/2012

Ribier A., Jean-thierry S. Process for the stabilization of vesicles of amphiphilic lipid(s) and composition for topical application containing the said stabilized vesicles. U.S. Patent US 6051250A

Handjani R, Ribier A, Vanlerberghe G, Zabotto S, Griat J. Cosmetic and pharmaceutical compositions containing niosomes and a water soluble polyamide, and a process for preparing these compositions. U.S. Patent US 4830857A

Jianfang F, Kaili H, Helong L, Mei L, Luting W. Drug-carrying precursor vesicle, preparation method and application thereof. CN105311638A

Singh A, Jain R. Targeted vesicular constructs for cytoprotection and treatment of H. pylori infections. WO2000042987A8

Young C, Lee W, Keith, Kwang-Ho. Pro-micelle pharmaceutical compositions. KR20040058196A

Abd-Elbary A, El-laithy HM, Tadros MI. A method for the preparation of nebulizable micronized niosomes of cromolyn sodium using nonionic surfactants. EG24388A