A Bird Eye View on Natural Gums and Mucilage used in Drug Delivery System
DOI:
https://doi.org/10.37285/ijpsn.2023.16.1.10Abstract
Natural mucilage is utilized in drug delivery systems (DDS) to accomplish a variety of duties, including directly or indirectly regulating the rate and amount of drug release in specific circumstances. Gums are biomolecules composed of carbohydrates that may attract water and form gels. Proteins and minerals are typically found in the creation of the gums. Gums exist in a number of types, including mucilage gums, seed gums, exudate gums, and others. Plant gums are among the most important gums because of their bioavailability. Excipients are being used in unique dosage forms to fill specific tasks as a result of advances in drug delivery technology. In some cases, these additives have a direct or indirect effect on the amount and/or rate of drug release and absorption. Given the present trend toward the use of natural goods derived from plants, the substitution of synthetic additives with natural ones is important. The world is getting increasingly interested in natural drugs and excipients. Natural mucilage has advantages over synthetic mucilage because it is more easily available, less expensive, and chemically inert. They now compete with several polymeric materials for use as diverse drugs and have advanced from being an excipient to cutting-edge drug carriers. Extensive research has gone into the development of safe and effective natural-based mucilage particulate drug delivery systems. Natural gums and mucilage are examined, as well as their isolation, purification, standardization, and characterization properties, as well as their applications. This article provides an overview of natural excipients used in both traditional dosage forms and innovative drug delivery systems.
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Gum, Mucilage, Novel drug delivery system, Bioavailability, Non-toxic
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