QbD based RP-HPLC Method Development and Validation for Estimation of Evogliptin Tartrate in Pharmaceutical Dosage Form
DOI:
https://doi.org/10.37285/ijpsn.2024.17.6.5Abstract
Result: The developed method was optimized with the help of response surface methodology such as BBD design in design expert software. This proposed method was validated as per ICH Q2 recommendation. With a correlation coefficient of 0.9935, the technique demonstrated linearity having 25-150 µg/mL concentration. Less than 2% RSD was reported for precision, while 99.81 - 99.95 % was found for accuracy.
Conclusion: It is possible to effectively use the proposed developed HPLC method for routine analysis of Evogliptin tartrate in tablet form since it was straightforward, accurate, and environmentally friendly.
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Keywords:
Evogliptin tartrate, Method Validation, RP-HPLC Method, Quality by Design. ANOVA study, DPP-IV inhibitorsPublished
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References
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