Synthesis of Some New Imidazo[1,2-b] Pyridazines

DOI:

https://doi.org/10.37285/ijpsn.2009.2.1.14

Authors

  • Sumakanth M.
  • V. Malla Reddy
  • V.S.H. Krishnan
  • B.S. Sastry

Abstract

Several 2,6-diaryl-imidazo[1,2-b]pyridazines (5 & 7) were prepared from 3-amino-6-aryl-pyridazines (3) which in turn were obtained from the corresponding 6-aryl-pyridazine-3(2H)-ones(1) via., 6-aryl-pyridazin-3(2H)-thiones (2) as intermediates, by a reaction with an appropriate a-halocarbonyl compounds (4) or a-haloacyl carbamates (6) in a suitable solvent at reflux temperature. The resulted products were characterized by their physical, analytical and spectral data.

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Keywords:

Imidazopyridazines, imidazocarbamates, phenacylbromide, chloroacetyl carbamate.

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Published

2009-05-31

How to Cite

1.
M. S, Reddy VM, Krishnan V, Sastry B. Synthesis of Some New Imidazo[1,2-b] Pyridazines. Scopus Indexed [Internet]. 2009 May 31 [cited 2024 Nov. 23];2(1):471-6. Available from: https://ijpsnonline.com/index.php/ijpsn/article/view/449

Issue

Vol. 2 No. 1 (2009): April-June 2009

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC

References

Abignents, E; Arena, F; Lurasche, E; Saturnio, S; F Formaco., 47, 931. through Chem. Abstr. 117, 225764.( 1992)

Antonia Sacchi; Sonia Laneri; Francesca arcna Marina; Eur. J. Med. Chem., 34, 1003. (1999)

Chafiq Hamdouchi; Concha Samchez; Martiniz; Joseph Cruber; Miriamdel Prade; J. Med. Chem., 46, 4333. (2003)

Comprehensive Heterocyclic Chemistry 1st edition 1984, 5, 607. Ber, A.E; Tschitschibabin, 58, 1704. (1925) Aust. J. Chem., 36, 1215. (1983)

Gordan, B; Barlin Les, P; Davis, Stephen J; Irlend; and Maria M. L Ngu; Aust. J. Chem., 42, 1735. (1989)

Gordan, B; Barlin Les, P; Davis; and Maria, M.L. Ngu; Aust. J. Chem., 42, 1749. (1989)

Gordan, B; Barlin, Les, P; Davis; Stephen J; Irlend and Maria M.. L. Ngu; And Jianko Zhang., Aust. J. Chem., 45, 731. (1992)

Gordan, B; Barlin, Les, P; Davis; Stephen, J; Irlend and Maria, M..L; Ngu; Aust. J. Chem., 42, 1133. (1989)

Gordan, B; Barlin, Les. P; Davis; and Maria, M.L Ngu; Aust. J. Chem., 41, 1149. (1988)

Gordan, B; Barlin, Les. P; Davis; Stephen, J; Irlend and Maria M. L. Ngu; And Schwemlein., Aust. J. Chem., 50, 91. (1997)

Hodgson, S.T; Jentins, D.C; Knick;. Rapson, E; and Watts, S. D. M; Bioorg. Med. Chem. Lett., 2, 1257. (1992)