Synthesis of Some New Imidazo[1,2-b] Pyridazines
DOI:
https://doi.org/10.37285/ijpsn.2009.2.1.14Abstract
Several 2,6-diaryl-imidazo[1,2-b]pyridazines (5 & 7) were prepared from 3-amino-6-aryl-pyridazines (3) which in turn were obtained from the corresponding 6-aryl-pyridazine-3(2H)-ones(1) via., 6-aryl-pyridazin-3(2H)-thiones (2) as intermediates, by a reaction with an appropriate a-halocarbonyl compounds (4) or a-haloacyl carbamates (6) in a suitable solvent at reflux temperature. The resulted products were characterized by their physical, analytical and spectral data.
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Keywords:
Imidazopyridazines, imidazocarbamates, phenacylbromide, chloroacetyl carbamate.Downloads
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