Synthesis and Anti-platelet Activity of 3-phenyl-4(1H)-quinolones

DOI:

https://doi.org/10.37285/ijpsn.2010.3.1.12

Authors

  • Achaiah Garlapati
  • Aruna G
  • Saritha Jyostna T

Abstract

A series of substituted 3-phenyl-4(1H)-quinolones and their 4-alkoxy derivatives have been prepared and evaluated for antiplatelet activity. Among the series compound IVb1 with 5-ethyl substituent and 4-methoxy group showed greater potency (IC50 = 13.29 µM) when compared to Aspirin (IC50 = 28.10 µM).

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Published

2010-05-31

How to Cite

1.
Garlapati A, G A, T SJ. Synthesis and Anti-platelet Activity of 3-phenyl-4(1H)-quinolones. Scopus Indexed [Internet]. 2010 May 31 [cited 2024 Dec. 21];3(1):877-80. Available from: https://ijpsnonline.com/index.php/ijpsn/article/view/480

Issue

Vol. 3 No. 1 (2010): April-June 2010

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC

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