Targeting Potential of Zinc Oxide Nanoparticles and Finasteride-loaded Nano Lipidic Carriers-infused Topical Gel - In vitro and In vivo Skin Permeation Studies
DOI:
https://doi.org/10.37285/ijpsn.2024.17.1.11Abstract
Dear Editor
I was going through the article with the above mentioned title which seems to be novel and imperative. Finasteride (FIN), an Inhibitor of the 5α reductase enzyme primarily utilized orally to treat androgenic alopecia, has been explored in a topical gel form. There options for treating androgenic alopecia are limited and the severe systemic adverse effects make things worse. This article highlighted lipidic nanocarriers offer numerous potential benefits like improved follicular permeability and solubility
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Finasteride nanolipidic carrierPublished
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Shweta Ramkar, Preeti K. Suresh. Finasteride-loaded nano-lipidic carriers for follicular drug delivery:preformulation screening and Box-Behnken experimental design for optimization of variables
Heliyon 8 (2022) e1017
Mohd Yasir,, Madhu Verma , Alok Pratap Singh. Nanostructured Lipid Carriers: A Groundbreaking Approach for Transdermal Drug Delivery. Adv Pharm Bull. 2020;10(2): 150-165.