Synthesis and Biological Evaluation of Novel 4-Ethyl-3-methyl-N-phenyl-3,4- dihydroquinoxalin-2-amine Derivatives"
DOI:
https://doi.org/10.37285/ijpsn.2010.3.4.12Abstract
Substituted anilines were reacted with ethyl-2-bromopropionate to give different substituted 2-bromo-N-phenylpropionamides, which were further condensed with o-phenylenediamines to give corresponding 3-methyl-N-phenyl-3,4-dihydroquinoxalin-2-amines. 4-ethyl-3-methyl-N-phenyl-3,4-dihydroquinoxalin-2-amines were synthesized by the N-alkylation of 3-methyl-N-phenyl-3,4
2-bromo-N-phenylpropionamides;
-dihydroquinoxalin-2-amines using ethyl iodide.
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Keywords:
Substituted anilines, 2-bromo-N-phenylpropionamides;
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