Conventional and Microwave Assisted Synthesis of New Pyran, Cyanopyran Schiffs Bases and their Anti-microbial Activities

Abstract

Ethyl2-amino-4-(4-chlorophenyl)-6-(4-methylphenyl)-4H-pyran-3-carboxylate and 2-amino-4-(4-chlorophenyl)-6-(4-methylphenyl)-4H-pyran-3-carbonitrile and their respective Schiffs bases were prepared by conventional and microwave methods. The required α, β - unsaturated ketone (chalcone) were prepared by the Claisen-Schmidt reaction using appropriate aromatic aldehyde and me